Cajun Chicken Alfredo Veggie Bake

Featured in: Global Comfort Food

Enjoy a savory blend of Cajun-spiced chicken, colorful vegetables, and creamy Alfredo sauce all baked together until bubbly and golden. This comforting main dish pairs tender pan-seared chicken with pasta and sautéed veggies, enveloped in a homemade Alfredo sauce and finished with a cheesy, parsley-topped crust. Ideal for family dinners, it delivers a balanced combination of spice, richness, and satisfying texture. Serve alongside a fresh salad and chilled white wine for a complete meal packed with Southern-inspired flavor.

Updated on Fri, 24 Oct 2025 07:38:07 GMT
Golden-brown Cajun Chicken Alfredo Veggie Bake with bubbly cheese, ready for a satisfying dinner. Save
Golden-brown Cajun Chicken Alfredo Veggie Bake with bubbly cheese, ready for a satisfying dinner. | forkina.com

This Cajun Chicken Alfredo Veggie Bake brings together cozy comfort and bold flavor for the ultimate crowd-pleasing casserole night. Juicy Cajun-spiced chicken mingles with a medley of vibrant roasted vegetables and perfectly cooked pasta, all wrapped up in a silky, homemade Alfredo sauce. Golden cheese tops it off for a bubbly, irresistible finish with every bite.

When I first put this dish together, my kids could not stop picking the crispy edges off the top before dinner was even served. Now it is a regular request for cozy Sunday nights or weeknight gatherings.

Ingredients

  • Boneless skinless chicken breasts: Opt for plump and fresh or high-quality pre-trimmed fillets for tenderness and flavor
  • Cajun seasoning: Essential for that signature heat and earthy kick Use your favorite blend or make your own for control over the spice level
  • Olive oil: Helps brown the chicken evenly and adds flavor Choose extra virgin for best richness
  • Red and yellow bell peppers: Choose firm glossy peppers for sweetness and color that brightens the dish
  • Zucchini: Adds moisture and a delicate squash flavor Pick small to medium zucchinis for tenderness
  • Red onion: Provides mild pungency and sweetens slightly when roasted Look for onions with tight skin and no soft spots
  • Broccoli florets: Adds a hearty bite and green goodness Use fresh firm florets for best texture
  • Garlic: Fresh cloves infuse savory flavor throughout Crush just before cooking for the best aroma
  • Penne or rigatoni: Pasta shapes with grooves or ridges hold onto the creamy sauce better Use a high-quality dry pasta for al dente bite
  • Unsalted butter: The base of Alfredo sauce for pure creamy richness
  • All-purpose flour: Thickens the sauce to coat every bite Make sure it is fresh for smooth blending
  • Whole milk and heavy cream: A blend for luscious silky texture Use dairy that is as fresh as possible for best flavor
  • Parmesan cheese: Gives Alfredo its signature nutty depth Grate it yourself for a meltier texture and more flavor
  • Salt and black pepper: Simple seasoning to sharpen all the flavors
  • Smoked paprika: Optional but adds a subtle smokiness Opt for Spanish smoked paprika for authenticity
  • Shredded mozzarella cheese: Melts into a gooey bubbling golden layer Use part-skim or whole milk for different melt and flavor
  • Fresh parsley: Garnish for color and a pop of freshness Use flat-leaf for best taste

Instructions

Preheat and Prepare the Dish:
Get your oven ready at 200°C or 400°F and lightly grease your baking dish with a little oil Spread evenly to prevent any sticking during baking
Sear and Dice the Chicken:
Season chicken breasts generously with the Cajun spice mix Press the seasoning on for full coverage In a large skillet over medium-high heat add oil then cook the chicken for about six or seven minutes each side Make sure the meat feels firm and juices run clear Let the chicken rest so it stays juicy then cut it into hearty bite-sized pieces
Cook the Pasta:
Bring a big pot of salted water to a rolling boil The pasta should be cooked just shy of done so it holds up once baked Drain the pasta well to avoid watering down your sauce
Sauté the Veggies:
In the same skillet add a splash more oil if needed Toss in peppers zucchini onion broccoli and minced garlic Sauté for four to five minutes so veggies get tender but still have some color and snap Remove them so they do not overcook
Make the Alfredo Sauce:
Heat butter in a saucepan over medium Stir in flour and cook for about a minute until you get a smooth blond roux Slowly pour in milk and cream whisking constantly to avoid lumps Keep stirring for several minutes as the mixture thickens Just when it coats the back of a spoon add Parmesan salt pepper and smoked paprika Stir until the cheese is fully melted into a glossy sauce
Combine and Assemble:
In a big mixing bowl blend cooked pasta with chicken sautéed vegetables and warm Alfredo sauce Mix until everything is nicely coated and evenly distributed Spoon this mixture into your prepared baking dish for even layers
Top and Bake:
Sprinkle mozzarella and extra Parmesan evenly over the top This ensures gooey meltiness and a crisp brown finish Slide it into the oven and bake for twenty to twenty-five minutes Watch for the top to bubble and turn golden with a little crisp at the edges
Rest and Garnish:
After baking let your casserole sit for about five minutes This makes it easier to serve Top with fresh chopped parsley just before bringing it to the table
Close-up of creamy Cajun Chicken Alfredo Veggie Bake, featuring tender chicken and vibrant vegetables. Pin it
Close-up of creamy Cajun Chicken Alfredo Veggie Bake, featuring tender chicken and vibrant vegetables. | forkina.com

Parmesan is hands-down my favorite part of this dish It is the flavor backbone giving every scoop that crave-worthy savoriness When my family gathers for seconds everyone makes sure to get the cheesiest corner

Storage Tips

Let leftovers cool completely before transferring to an airtight container This bake will keep well in the fridge for up to three days Reheat covered in the oven or microwave with a splash of milk to loosen the sauce If you want to freeze portion before baking for best results or reheat straight from the freezer with extra time

Ingredient Substitutions

No heavy cream Use half and half or just whole milk for a lighter sauce Switch up vegetables with whatever is peak season in your market like asparagus or mushrooms For gluten-free needs sub lentil or chickpea-based pasta If chicken is not an option use turkey or even shrimp for a seafood twist

Serving Suggestions

This hearty casserole is pretty much a meal in itself Pair it with crisp green salads or garlicky roasted broccoli for even more veggie goodness A cold glass of Chardonnay or unsweetened iced tea fits perfectly with its creamy and spicy vibes

Cultural Roots

While classic Alfredo is Italian Cajun cuisine brings together spice and soul food elements This bake mashes up creaminess and heat in true American comfort food spirit My first Cajun-inspired pasta bake happened after a dinner out in New Orleans and I have been hooked on the combo ever since

Seasonal Adaptations

Swap the vegetable mix for butternut squash and kale in the fall In summer try cherry tomatoes or snap peas Go lighter with less cream in spring and extra herbs year-round

Serving spoon scoops into flavorful veggie-packed Cajun Chicken Alfredo Bake; a perfect family meal. Pin it
Serving spoon scoops into flavorful veggie-packed Cajun Chicken Alfredo Bake; a perfect family meal. | forkina.com

This recipe is very forgiving so you can throw in whatever needs using up Baking in advance makes it perfect for potlucks or busy weeknights Letting it rest before serving gives you neater slices and richer flavor

Frequently Asked Questions

What type of pasta works best?

Penne or rigatoni hold up well, but rotini or fusilli can also be used for a similar effect.

Can I substitute the chicken?

Yes, try turkey, shrimp, sausage, or keep it vegetarian by omitting meat and adding more veggies.

Is the Alfredo sauce homemade?

Yes, this dish uses a simple homemade Alfredo sauce with butter, flour, milk, cream, and Parmesan.

How can I make it spicier?

Add cayenne pepper, extra Cajun seasoning, or sliced jalapeños for more heat.

What sides pair well?

A crisp green salad, garlic bread, or roasted asparagus complement the creamy and spicy flavors.

Can I make it ahead?

Prepare, assemble, and refrigerate before baking. Bake when ready to serve, adding 5–10 minutes if chilled.

Cajun Chicken Alfredo Veggie Bake

Spicy Cajun chicken, roasted vegetables, Alfredo sauce, and pasta baked together for creamy comfort.

Prep Time
25 Minutes
Cook Time
35 Minutes
Total Time
60 Minutes


Difficulty: Medium

Cuisine: American (Cajun-inspired)

Yield: 4 servings

Dietary: None specified

Ingredients

Chicken

01 2 large boneless, skinless chicken breasts (about 18 oz)
02 1 tablespoon Cajun seasoning
03 1 tablespoon olive oil

Vegetables

01 1 red bell pepper, diced
02 1 yellow bell pepper, diced
03 1 small zucchini, sliced
04 1 small red onion, chopped
05 1 cup broccoli florets
06 2 cloves garlic, minced

Pasta

01 9 oz penne or rigatoni

Alfredo Sauce

01 2 tablespoons unsalted butter
02 2 tablespoons all-purpose flour
03 1 1/2 cups whole milk
04 1 cup heavy cream
05 1 cup grated Parmesan cheese
06 1/2 teaspoon salt
07 1/4 teaspoon black pepper
08 1/4 teaspoon smoked paprika (optional)

Topping

01 1/2 cup shredded mozzarella cheese
02 1/4 cup grated Parmesan cheese
03 2 tablespoons chopped fresh parsley

Instructions

Step 01

Oven Preparation: Preheat oven to 400°F. Lightly grease a 9x13-inch baking dish.

Step 02

Chicken Cooking: Season chicken breasts evenly with Cajun seasoning. In a large skillet over medium-high heat, warm olive oil. Add chicken and cook for 6–7 minutes per side until fully cooked. Let chicken rest for 5 minutes, then dice into bite-sized portions.

Step 03

Pasta Cooking: Bring a large pot of salted water to a boil. Cook pasta according to package directions until al dente. Drain thoroughly and set aside.

Step 04

Vegetable Sautéing: In the same skillet, add additional olive oil if necessary. Sauté red and yellow bell peppers, zucchini, red onion, broccoli florets, and garlic for 4–5 minutes until just tender and vibrant. Remove vegetables from heat.

Step 05

Alfredo Sauce Preparation: In a saucepan over medium heat, melt butter. Whisk in flour and cook for 1 minute. Gradually incorporate milk and cream while whisking until sauce becomes smooth and thickened, roughly 4–5 minutes. Stir in Parmesan, salt, black pepper, and smoked paprika until cheese has melted.

Step 06

Combine Components: In a large mixing bowl, combine cooked pasta, diced chicken, sautéed vegetables, and Alfredo sauce. Mix until thoroughly coated. Transfer mixture into prepared baking dish.

Step 07

Add Cheese Topping: Evenly sprinkle shredded mozzarella and grated Parmesan over the surface of the bake.

Step 08

Baking: Bake uncovered for 20–25 minutes until bubbly and golden brown on top.

Step 09

Finishing and Servings: Remove dish from oven and allow to rest for 5 minutes. Garnish with chopped parsley before serving.

Tools You'll Need

  • Large skillet
  • Saucepan
  • Large pot
  • 9x13-inch baking dish
  • Whisk
  • Mixing bowls
  • Chef’s knife

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Contains milk (dairy), wheat (gluten), eggs (may be present in pasta).
  • Verify pasta and cheese ingredients for potential hidden allergens.

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 650
  • Total Fat: 32 g
  • Total Carbohydrate: 55 g
  • Protein: 38 g